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Jacqueline Y. Channon Smith, PHD

Assistant Professor of Microbiology and Immunology

Additional Titles/Positions/Affiliations:
DartLab Director

Microbiology and Immunology

U. London, PhD 1984
U. Auckland, BS 1972

Dr. Channon Smith received her B.Sc. from the University of Auckland in 1972, and her Ph.D. from the University of London in 1984. After postdoctoral work as an NIH research fellow and research associate in the Department of Pediatrics at the National Jewish Center for Immunology and Respiratory Disease and the Department of Microbiology at Dartmouth Medical School, Dr. Channon Smith joined the faculty of the Department of Microbiology at Dartmouth Medical School in 1994.

Norris Cotton Cancer Center


Contact Information:

Dartmouth Medical School
Rubin Bldg. HB 7937
1 Medical Center Dr
Lebanon NH 03756

Office: 722 Rubin
Phone: 603-653-9916
Fax: 603-653-9900
Email: jacqueline.smith@dartmouth.edu

Assistant: Alan Bergeron
Asst. Phone: 603-653-9914
Asst. Email: ajb@dartmouth.edu

Professional Interests:

Jacqueline Y. Channon Smith, Ph.D.
Assistant Professor of Microbiology & Immunology

The Shared Resource (DartLab) provides blood isolation services, runs high complexity immunoassays, and customizes cutting edge immunoassays. All work complies with Good Laboratory Practices standards and includes rigorous Quality Assurance and Quality Control.

My current interests involve advancing technologies in multi-color flow cytometry, quality assurance, and flow cytometry education. I design functional assays and phenotyping panels to monitor the immune cells involved in clinical disease, correlating assay results to disease outcomes, with an emphasis on cancer.

Courses Taught:

Flow Cytometry

Selected Publications:


  • Barth RJ Jr, Fisher DA, Wallace PK, Channon JY, Noelle RJ, Gui J, Ernstoff MS. A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival. Clin Cancer Res. 2010 16:5548-56 (view details on MedLine)

  • Talebian L, Fischer DA, Wu J, Channon JY, Sentman CL, Ernstoff MS, Meehan KR. The natural killer-activating receptor, NKG2D, on CD3+CD8+ T cells plays a critical role in identifying and killing autologous myeloma cells. Transfusion. 2014 54:1515-21 (view details on MedLine)

  • Fahey JV, Schaefer TM, Channon JY, Wira CR. Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract. Hum Reprod. 2005 2:1439-46 (view details on MedLine)

  • Channon, J.Y. and Leslie, C.C. A calcium-dependent mechanism for associating a soluble arachidonyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7. J. Biol. Chem. 1990 265:5409-5413 1990 (view details on MedLine)

  • Blackwell, J.M., Ezekowitz, R.A.B., Roberts, M.B., Channon, J.Y., Sim, R.B. and Gordon, S. Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum. J. Exp. Med. 1985 162:324-331 (view details on MedLine)