Publications
Park G, Servin JA, Turner GE, Altamirano L, Colot HV, Collopy P, Litvinkova L, Li L, Jones CA, Diala FG, Dunlap JC, Borkovich KA
Global analysis of serine-threonine protein kinase genes in Neurospora crassa.
Eukaryot Cell 2011 Nov; 10(11):1553-64
PMID: 21965514
Vaidya AT, Chen CH, Dunlap JC, Loros JJ, Crane BR
Structure of a light-activated LOV protein dimer that regulates transcription.
Sci Signal 2011 Aug 2; 4(184):ra50
PMID: 21868352
Belden WJ, Lewis ZA, Selker EU, Loros JJ, Dunlap JC
CHD1 remodels chromatin and influences transient DNA methylation at the clock gene frequency.
PLoS Genet 2011 Jul; 7(7):e1002166
PMID: 21811413
Baker CL, Loros JJ, Dunlap JC
The circadian clock of Neurospora crassa.
FEMS Microbiol Rev 2012 Jan; 36(1):95-110
PMID: 21707668
Poliandri AH, Gamsby JJ, Christian M, Spinella MJ, Loros JJ, Dunlap JC, Parker MG
Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).
J Biol Rhythms 2011 Jun; 26(3):187-99
PMID: 21628546
Park G, Colot HV, Collopy PD, Krystofova S, Crew C, Ringelberg C, Litvinkova L, Altamirano L, Li L, Curilla S, Wang W, Gorrochotegui-Escalante N, Dunlap JC, Borkovich KA
High-throughput production of gene replacement mutants in Neurospora crassa.
Methods Mol Biol 2011; 722:179-89
PMID: 21590421
Chen CH, DeMay BS, Gladfelter AS, Dunlap JC, Loros JJ
Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora.
Proc Natl Acad Sci U S A 2010 Sep 21; 107(38):16715-20
PMID: 20733070
Chen CH, Dunlap JC, Loros JJ
Neurospora illuminates fungal photoreception.
Fungal Genet Biol 2010 Nov; 47(11):922-9
PMID: 20637887
Froehlich AC, Chen CH, Belden WJ, Madeti C, Roenneberg T, Merrow M, Loros JJ, Dunlap JC
Genetic and molecular characterization of a cryptochrome from the filamentous fungus Neurospora crassa.
Eukaryot Cell 2010 May; 9(5):738-50
PMID: 20305004
Collopy PD, Colot HV, Park G, Ringelberg C, Crew CM, Borkovich KA, Dunlap JC
High-throughput construction of gene deletion cassettes for generation of Neurospora crassa knockout strains.
Methods Mol Biol 2010; 638:33-40
PMID: 20238259
Baker CL, Dunlap JC
Circadian rhythms: phosphorylating the CLOCK.
Cell Cycle 2010 Jan 15; 9(2):231-2
PMID: 20061797
Shi M, Collett M, Loros JJ, Dunlap JC
FRQ-interacting RNA helicase mediates negative and positive feedback in the Neurospora circadian clock.
Genetics 2010 Feb; 184(2):351-61
PMID: 19948888
Chen CH, Loros JJ
Neurospora sees the light: light signaling components in a model system.
Commun Integr Biol 2009 Sep; 2(5):448-51
PMID: 19907715
Heim KC, Gamsby JJ, Hever MP, Freemantle SJ, Loros JJ, Dunlap JC, Spinella MJ
Retinoic acid mediates long-paced oscillations in retinoid receptor activity: evidence for a potential role for RIP140.
PLoS One 2009 Oct 28; 4(10):e7639
PMID: 19862326
Mehra A, Baker CL, Loros JJ, Dunlap JC
Post-translational modifications in circadian rhythms.
Trends Biochem Sci 2009 Oct; 34(10):483-90
PMID: 19740663
Gamsby JJ, Loros JJ, Dunlap JC
A phylogenetically conserved DNA damage response resets the circadian clock.
J Biol Rhythms 2009 Jun; 24(3):193-202
PMID: 19465696
Baker CL, Kettenbach AN, Loros JJ, Gerber SA, Dunlap JC
Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock.
Mol Cell 2009 May 15; 34(3):354-63
PMID: 19450533
Mehra A, Shi M, Baker CL, Colot HV, Loros JJ, Dunlap JC
A role for casein kinase 2 in the mechanism underlying circadian temperature compensation.
Cell 2009 May 15; 137(4):749-60
PMID: 19450520
Larrondo LF, Colot HV, Baker CL, Loros JJ, Dunlap JC
Fungal functional genomics: tunable knockout-knock-in expression and tagging strategies.
Eukaryot Cell 2009 May; 8(5):800-4
PMID: 19286985
Chen CH, Ringelberg CS, Gross RH, Dunlap JC, Loros JJ
Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora.
EMBO J 2009 Apr 22; 28(8):1029-42
PMID: 19262566
Duffield GE, Watson NP, Mantani A, Peirson SN, Robles-Murguia M, Loros JJ, Israel MA, Dunlap JC
A role for Id2 in regulating photic entrainment of the mammalian circadian system.
Curr Biol 2009 Feb 24; 19(4):297-304
PMID: 19217292
Lambreghts R, Shi M, Belden WJ, Decaprio D, Park D, Henn MR, Galagan JE, Basturkmen M, Birren BW, Sachs MS, Dunlap JC, Loros JJ
A high-density single nucleotide polymorphism map for Neurospora crassa.
Genetics 2009 Feb; 181(2):767-81
PMID: 19015548
Hong CI, Ruoff P, Loros JJ, Dunlap JC
Closing the circadian negative feedback loop: FRQ-dependent clearance of WC-1 from the nucleus.
Genes Dev 2008 Nov 15; 22(22):3196-204
PMID: 18997062
Belden WJ, Dunlap JC
SIRT1 is a circadian deacetylase for core clock components.
Cell 2008 Jul 25; 134(2):212-4
PMID: 18662537
Dunlap JC
Salad days in the rhythms trade.
Genetics 2008 Jan; 178(1):1-13
PMID: 18202353
Shi M, Larrondo LF, Loros JJ, Dunlap JC
A developmental cycle masks output from the circadian oscillator under conditions of choline deficiency in Neurospora.
Proc Natl Acad Sci U S A 2007 Dec 11; 104(50):20102-7
PMID: 18056807
Diernfellner A, Colot HV, Dintsis O, Loros JJ, Dunlap JC, Brunner M
Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.
FEBS Lett 2007 Dec 22; 581(30):5759-64
PMID: 18037381
Hong CI, Jolma IW, Loros JJ, Dunlap JC, Ruoff P
Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock.
Biophys J 2008 Feb 15; 94(4):1221-32
PMID: 17965132
Gooch VD, Mehra A, Larrondo LF, Fox J, Touroutoutoudis M, Loros JJ, Dunlap JC
Fully codon-optimized luciferase uncovers novel temperature characteristics of the Neurospora clock.
Eukaryot Cell 2008 Jan; 7(1):28-37
PMID: 17766461
Belden WJ, Larrondo LF, Froehlich AC, Shi M, Chen CH, Loros JJ, Dunlap JC
The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output.
Genes Dev 2007 Jun 15; 21(12):1494-505
PMID: 17575051
Zoltowski BD, Schwerdtfeger C, Widom J, Loros JJ, Bilwes AM, Dunlap JC, Crane BR
Conformational switching in the fungal light sensor Vivid.
Science 2007 May 18; 316(5827):1054-7
PMID: 17510367
Nowrousian M, Frank S, Koers S, Strauch P, Weitner T, Ringelberg C, Dunlap JC, Loros JJ, Kuck U
The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora.
Mol Microbiol 2007 May; 64(4):923-37
PMID: 17501918
Dunlap JC, Borkovich KA, Henn MR, Turner GE, Sachs MS, Glass NL, McCluskey K, Plamann M, Galagan JE, Birren BW, Weiss RL, Townsend JP, Loros JJ, Nelson MA, Lambreghts R, Colot HV, Park G, Collopy P, Ringelberg C, Crew C, Litvinkova L, DeCaprio D, Hood HM, Curilla S, Shi M, Crawford M, Koerhsen M, Montgomery P, Larson L, Pearson M, Kasuga T, Tian C, Başturkmen M, Altamirano L, Xu J
Enabling a community to dissect an organism: overview of the Neurospora functional genomics project.
Adv Genet 2007; 57:49-96
PMID: 17352902
Belden WJ, Loros JJ, Dunlap JC
Execution of the circadian negative feedback loop in Neurospora requires the ATP-dependent chromatin-remodeling enzyme CLOCKSWITCH.
Mol Cell 2007 Feb 23; 25(4):587-600
PMID: 17317630
Dunlap JC, Loros JJ
How fungi keep time: circadian system in Neurospora and other fungi.
Curr Opin Microbiol 2006 Dec; 9(6):579-87
PMID: 17064954
Belden WJ, Loros JJ, Dunlap JC
CLOCK leaves its mark on histones.
Trends Biochem Sci 2006 Nov; 31(11):610-3
PMID: 17027273
Dunlap JC
Proteins in the Neurospora circadian clockworks.
J Biol Chem 2006 Sep 29; 281(39):28489-93
PMID: 16905532
Mehra A, Hong CI, Shi M, Loros JJ, Dunlap JC, Ruoff P
Circadian rhythmicity by autocatalysis.
PLoS Comput Biol 2006 Jul 28; 2(7):e96
PMID: 16863394
Pregueiro AM, Liu Q, Baker CL, Dunlap JC, Loros JJ
The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles.
Science 2006 Aug 4; 313(5787):644-9
PMID: 16809488
Colot HV, Park G, Turner GE, Ringelberg C, Crew CM, Litvinkova L, Weiss RL, Borkovich KA, Dunlap JC
A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors.
Proc Natl Acad Sci U S A 2006 Jul 5; 103(27):10352-7
PMID: 16801547
Dunlap JC
Physiology. Running a clock requires quality time together.
Science 2006 Jan 13; 311(5758):184-6
PMID: 16410512
Froehlich AC, Noh B, Vierstra RD, Loros J, Dunlap JC
Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassa.
Eukaryot Cell 2005 Dec; 4(12):2140-52
PMID: 16339731
Ruoff P, Loros JJ, Dunlap JC
The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock.
Proc Natl Acad Sci U S A 2005 Dec 6; 102(49):17681-6
PMID: 16314576
Elvin M, Loros JJ, Dunlap JC, Heintzen C
The PAS/LOV protein VIVID supports a rapidly dampened daytime oscillator that facilitates entrainment of the Neurospora circadian clock.
Genes Dev 2005 Nov 1; 19(21):2593-605
PMID: 16264193
Colot HV, Loros JJ, Dunlap JC
Temperature-modulated alternative splicing and promoter use in the Circadian clock gene frequency.
Mol Biol Cell 2005 Dec; 16(12):5563-71
PMID: 16195340
Duffield G, Loros JJ, Dunlap JC
Analysis of circadian output rhythms of gene expression in Neurospora and mammalian cells in culture.
Methods Enzymol 2005; 393:315-41
PMID: 15817297
Dunlap JC, Loros JJ
Analysis of circadian rhythms in Neurospora: overview of assays and genetic and molecular biological manipulation.
Methods Enzymol 2005; 393:3-22
PMID: 15817284
Nowrousian M, Ringelberg C, Dunlap JC, Loros JJ, Kuck U
Cross-species microarray hybridization to identify developmentally regulated genes in the filamentous fungus Sordaria macrospora.
Mol Genet Genomics 2005 Apr; 273(2):137-49
PMID: 15778868
Pregueiro AM, Price-Lloyd N, Bell-Pedersen D, Heintzen C, Loros JJ, Dunlap JC
Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles.
Proc Natl Acad Sci U S A 2005 Feb 8; 102(6):2210-5
PMID: 15677317
Dunlap JC, Loros JJ
The neurospora circadian system.
J Biol Rhythms 2004 Oct; 19(5):414-24
PMID: 15534321
Christensen MK, Falkeid G, Loros JJ, Dunlap JC, Lillo C, Ruoff P
A nitrate-induced frq-less oscillator in Neurospora crassa.
J Biol Rhythms 2004 Aug; 19(4):280-6
PMID: 15245647
Borkovich KA, Alex LA, Yarden O, Freitag M, Turner GE, Read ND, Seiler S, Bell-Pedersen D, Paietta J, Plesofsky N, Plamann M, Goodrich-Tanrikulu M, Schulte U, Mannhaupt G, Nargang FE, Radford A, Selitrennikoff C, Galagan JE, Dunlap JC, Loros JJ, Catcheside D, Inoue H, Aramayo R, Polymenis M, Selker EU, Sachs MS, Marzluf GA, Paulsen I, Davis R, Ebbole DJ, Zelter A, Kalkman ER, O'Rourke R, Bowring F, Yeadon J, Ishii C, Suzuki K, Sakai W, Pratt R
Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism.
Microbiol Mol Biol Rev 2004 Mar; 68(1):1-108
PMID: 15007097
Dunlap JC
Kinases and circadian clocks: per goes it alone.
Dev Cell 2004 Feb; 6(2):160-1
PMID: 14960268
Froehlich AC, Pregueiro A, Lee K, Denault D, Colot H, Nowrousian M, Loros JJ, Dunlap JC
The molecular workings of the Neurospora biological clock.
Novartis Found Symp 2003; 253:184-98; discussion 102-9, 198-202, 281-4
PMID: 14712922
Nowrousian M, Duffield GE, Loros JJ, Dunlap JC
The frequency gene is required for temperature-dependent regulation of many clock-controlled genes in Neurospora crassa.
Genetics 2003 Jul; 164(3):923-33
PMID: 12871904
Froehlich AC, Loros JJ, Dunlap JC
Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY.
Proc Natl Acad Sci U S A 2003 May 13; 100(10):5914-9
PMID: 12714686
Kramer C, Loros JJ, Dunlap JC, Crosthwaite SK
Role for antisense RNA in regulating circadian clock function in Neurospora crassa.
Nature 2003 Feb 27; 421(6926):948-52
PMID: 12607002
Lee K, Dunlap JC, Loros JJ
Roles for WHITE COLLAR-1 in circadian and general photoperception in Neurospora crassa.
Genetics 2003 Jan; 163(1):103-14
PMID: 12586700
Shinohara ML, Correa A, Bell-Pedersen D, Dunlap JC, Loros JJ
Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development.
Eukaryot Cell 2002 Feb; 1(1):33-43
PMID: 12455969
Wu CT, Dunlap JC
Homology effects: the difference between 1 and 2.
Adv Genet 2002; 46:xvii-xxiii
PMID: 12136788
Froehlich AC, Liu Y, Loros JJ, Dunlap JC
White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter.
Science 2002 Aug 2; 297(5582):815-9
PMID: 12098706
Duffield GE, Best JD, Meurers BH, Bittner A, Loros JJ, Dunlap JC
Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells.
Curr Biol 2002 Apr 2; 12(7):551-7
PMID: 11937023
Collett MA, Garceau N, Dunlap JC, Loros JJ
Light and clock expression of the Neurospora clock gene frequency is differentially driven by but dependent on WHITE COLLAR-2.
Genetics 2002 Jan; 160(1):149-58
PMID: 11805052